HAPPE Spine Invested 2025

A medical biotech startup out of the University of Notre Dame, HAPPE Spine is the creator of the patented HAPPE material and manufacturing platform. Powered by this novel platform, HAPPE’s first medical device is the FDA-cleared INTEGRATE-C, the only inter-body fusion cage to offer cancellous porosity with fully integrated hydroxyapatite through the entire implant height, combined with radiolucency and bone-like mechanical properties. The device’s porosity and impregnation of hydroxyapatite on all surfaces promotes bone in-growth and on-growth. INTEGRATE-C is offered as an alternative to titanium implants and PEEK implants, both of which have limitations.

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